The latest nvidia Quadro 4000 drivers include support for the GTX 460, no need to edit any nvidia kexts.
-10.6.5 or higher required, use GraphicsEnabler=n until you're at 10.6.5 or higher, or when booting your install media.
-MacPro3,1, 4,1 or 5,1 model identifier required. If you're using a different model identifier, you can edit distribution.dist inside the installer .pkg and add it. Open the file in a text editor, the rest should be obvious.
-No OpenCL support (CUDA works but not all 336 CUDA cores are used)
-If you're experiencing freezes or kernel panics, leave VLC running in the background playing a video on repeat (this solution sucks).
-If Chameleon's GraphicsEnabler=y doesn't seem to work, set your PCI Root manually in /Extra/com.apple.Boot.plist (google it)
-If performance is exceptionally bad, use MacPro3,1 model identifier or edit AppleGraphicsPowerManagement.kext (google it)
-Here's how to get HDMI audio working:
http://www.projectosx.com/forum/index.php?...=465&st=118